Fig. 7
Model of MAPK signaling pathway in MAP3K1; MAP2K4 wild-type or mutant cells. a Schematic representation of cross-talk of the MEK-ERK and JNK signaling pathways. b MEK-ERK and JNK signaling pathways in MAP3K1;MAP2K4 wild-type (left) or mutant (right) tumors with MEK inhibitor treatment
