Fig. 4
From: Spatial transcriptomic survey of human embryonic cerebral cortex by single-cell RNA-seq analysis
Maturation degree of embryonic neurons is different from the adult neurons. a Heatmap showing the expression of marker genes identified in the adult neuron subtypes. b Expression of layer markers in different sub-clusters of excitatory neuron (left) and inhibitory neuron (right). c Landscape showing the maturity level of each region in the cortex measured by CUX2-positive excitatory neuron ratio. Regions of gray color are ruled out as they are detected with < 50 neurons. d In situ hybridization of CUX2 in PC and IT regions of a 22WF embryo. Scale bar, 100 μm. e Landscape showing the maturity level of each region in the cortex measured by expression level of synapse formation and function related genes
