Fig. 5

Expression of epigenetic modification-related genes and imprinted genes in the 14 cell subtypes. a Heatmap of the genes associated with DNA methylation and demethylation. b Immunofluorescence staining of the indicated molecules in the human placental villi at 8 weeks of pregnancy. The cells between the white and yellow dashed lines are CTBs. STR, stromal cells. c, d Heatmaps of the chromatin modification writers (c) and erasers (d) in each cell subtype