Fig. 7
From: Single-cell RNA-seq uncovers dynamic processes and critical regulators in mouse spermatogenesis
Dynamic expression patterns of sex chromosome-linked genes during spermatogenesis. a Boxplots showing the numbers of protein-coding genes on sex chromosomes expressed in each individual cell at 20 developmental stages. b Boxplots indicating the normalized UMI counts of protein-coding genes on sex chromosomes expressed in each individual cell at 20 developmental stages. c Heatmap showing five groups of sex chromosome-linked gene expression patterns. The colored bars on the left from top to bottom represent MSCI PMSC, MSCI escape PMSC, escape MSCI, RS specific, and other, respectively. The classification standard of five groups above, see Materials and Methods for details. Color key from yellow to blue represents the relative gene expression level from high to low. d GO analysis of escaped MSCI genes. e Bar plots showing X chromosome-linked (top panel) and Y chromosome-linked (bottom panel) gene expression levels in MI, MII, RS2, RS4, RS6, and RS8 stages. f Principal component analysis (PCA) showing the distribution of cells from RS2 and RS6 based on chromosome X (ChrX)-linked genes (top panel) and chromosome Y (ChrY)-linked genes (bottom panel)
