Fig. 2
Characterization of the m6A-bearing genes in TKI resistant cells. a Pie chart presenting fractions of m6A peaks in different transcript segments. CDS, coding sequence; UTR, untranslated region. b Venn diagram illustrating the number of overlapped genes between m6A containing and differentially-expressed gene profiles. c Enrichment scores for Gene Ontology (GO) categories in overlapped genes. The –log (p value) axis indicates the statistical significance of the functions to the dataset. d–g qPCR measuring the expression levels of indicated genes in TKI resistant vs parental K562, KU812, Kasumi-1 and MV4-11 cells. Data represent three independent experiments. h Coverage plot of m6A IP and input reads (without smoothing the curve). IP, immunoprecipitation; IP, blue; input, red. See also Figures S1 and S2
