Fig. 2: MiDAS peaks correspond to the borders of replicated/unreplicated genomic regions. | Cell Research

Fig. 2: MiDAS peaks correspond to the borders of replicated/unreplicated genomic regions.

From: High-resolution mapping of mitotic DNA synthesis regions and common fragile sites in the human genome through direct sequencing

Fig. 2

a, b Replication signal (green) around the WWOX gene at the indicated times after release from a thymidine block in the absence (a) or presence (b) of 0.4 µM aphidicolin. The MiDAS signal for the same genomic site is shown in purple in b. Bin resolution and ruler scale are as in Fig. 1b. c, d Genome-wide average replication signal at double-peak (left panels; span of genomic region, 2.9 Mb) and merged- and single-peak (right panels; span of genomic region, 2.3 Mb) MiDAS regions at the indicated times after release from a thymidine block in the absence (c) or presence (d) of 0.4 µM aphidicolin. Pk, peak.

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