Fig. 7: TF network and dynamics of cell cycle state along with ILC specialization.
From: Delineating spatiotemporal and hierarchical development of human fetal innate lymphoid cells
a t-SNE visualization of ILCP from Fig. 2a, Pre-ILC1 from Fig. 4a, Pre-ILC2 from Fig. 5a and Pre-ILC3 from Fig. 6a. b Violin plots show the expression of featured TF-encoding genes in different cell clusters. c The correlation network of TFs of ILCP and three Pre-ILCs. All TFs in each cluster were used to construct network; nodes (TFs) with more than 3 edges are shown. Colors indicate cell types (a–c). d Fully annotated STEMNET map visualizes fate probabilities of progenitors toward mature NK, ILC1, ILC2 and ILC3 cells. Colors indicate cell types (upper panel) and the possibility of progenitor cells developing into the corresponding lineage (below panel). e Visualization of the probabilities of different progenitors and precursors to develop toward the specific lineages. Colors indicate cell types. f Proportions of the cells with different cell cycle statuses in each cluster are shown in bar graph. Colors represent cell cycle statues. g Heatmap of pearson correlation matrix among ILCP and three Pre-ILCs. Colors indicate correlation coefficient.
