Fig. 2: Overall structure of the IR subunit from the X. laevis NPC.
From: Cryo-EM structure of the inner ring from the Xenopus laevis nuclear pore complex
a Overall EM map of the IR subunit from X. laevis NPC. Two perpendicular views are shown. The IR subunit displays a 2-fold symmetry, with a cytoplasmic half and a nuclear half. The EM maps for individual nucleoporins in each half are color-coded identically. The NE is shown in gray, the two layer-like density representing lipid bilayer of NE is apparent in the right panel. b Structure of the IR subunit from the X. laevis NPC. Two views are shown. In the left panel, individual nucleoporins are color-coded. In the right panel, nucleoporins of the nuclear half are colored gray; different copies of the same protein in the cytoplasmic half are differentially colored. c Overall structure of the IR subunit from X. laevis NPC. Top and bottom: the overall structure of the IR subunit is displayed in two perpendicular views (first column from left). For each view, the IR subunit is disseminated into three layers: ten molecules of Nup155/ALADIN/NDC1 close to the NE (second column from left), the central scaffold of eight molecules of Nup188/Nup205/Nup93 (third column from left), and four CNTs (fourth column from left).
