Fig. 1: Nucleosome occupancy is quickly established in mouse male pronuclei after fertilization. | Cell Research

Fig. 1: Nucleosome occupancy is quickly established in mouse male pronuclei after fertilization.

From: Dynamic nucleosome organization after fertilization reveals regulatory factors for mouse zygotic genome activation

Fig. 1

a Schematic representation showing the collection of pronucleus samples for ULI-MNase-seq. b Confocal microscopy images of H2B-RFP mRNA-injected embryos shortly after fertilization. Newly incorporated H2B was present in the male PN (arrowhead) as early as 1 hpf. c Bar plots showing the fraction of nucleosome-occupied 1-kb bins in each PN sample. Error bars represent 1.96 × SD. d Line charts showing the fraction of nucleosome-occupied 1-kb bins in sex chromosomes and autosomes of each PN and ESC samples. Chr, chromosome.

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