Fig. 4: A CN1 accelerated region is under positive selection in Asian Population.
From: The complete and fully-phased diploid genome of a male Han Chinese
a Alignment of chr3:57,237,838–57,237,868 sequences of CN1, chimpanzee and the haplotypes from different super-populations. Dots indicate identical base alignment. b Fst (EAS vs EUR and EAS vs AFR) scores around CN1 chr3:57,237,838–57,237,868 (red line) and its flanking region (window = 10 kb, step size = 2 kb). Blue dashed lines indicate the Fst cutoff with P < 0.05. c Global map shows the distribution of CN1 and CHM13/HG01891 haplotype frequency in 75 populations. The color and size of the circles represent the haplotype and the number of haplotypes, respectively. African, American, East Asian, European, Middle Eastern, Oceanian, and South Asian are denoted as AFR, AMR, EAS, EUR, MEA, OCE, and SAS, respectively. d Haplotype network of CN1 chr3:57,237,838–57,237,868. Most CN1-type haplotypes are found in EAS, while most CHM13/HG01891-type haplotypes are found in AFR. The color and size of the circles represent the super-population and the number of haplotypes, respectively.
