Fig. 5: Cryo-EM structure of the ISFba1 TnpB–reRNA–dsDNA complex.
From: Discovery and structural mechanism of DNA endonucleases guided by RAGATH-18-derived RNAs
a Domain organization of ISFba1 TnpB. TID, TAM-interacting domain; REC, recognition domain. TID and RuvC domains are separated into two and three segments, respectively. b, c Cryo-EM reconstruction at 3.0 Å (b) and cartoon representations of the ISFba1 TnpB–reRNA–dsDNA complex (c).
