Fig. 4: Biological functions of migrasomes.
From: A decade of migrasome research: biogenesis, physiological functions, and disease implications
Migrasomes participate in diverse physiological processes through multiple mechanisms: a localized secretion of signaling molecules; b targeted delivery of signaling cues via detached migrasomes, contributing to the formation of spatially defined signaling centers and gradients during embryonic development, angiogenesis, and immune responses; c intercellular transfer of proteins and RNAs between neighboring cells, fostering cell–cell communication; d maintenance of cellular homeostasis under stress conditions by expelling damaged organelles; e absorption and targeted delivery of coagulation factors to promote clotting.
