Fig. 2: CBFβ is specifically induced by IFN-λ. | Cellular & Molecular Immunology

Fig. 2: CBFβ is specifically induced by IFN-λ.

From: Type III interferon-induced CBFβ inhibits HBV replication by hijacking HBx

Fig. 2

a, b HepG2 cells were treated with IFN-α or IFN-β as indicated. Whole-cell lysates were immunoblotted with CBFβ, IFIT2, or GAPDH antibodies, and RNA was extracted and subjected to Q-PCR analysis to measure the CBFβ or IFIT2 expression. c HepG2 cells were treated with IFN-γ as in a, b, and analyzed as in a, b. d HepG2 cells were treated with IFN-λ1 as in a, b, and analyzed as in a, b. All of the data are from three pooled independent experiments and are shown as the mean ± s.d. Student’s t-test was performed. *p < 0.05, **p < 0.01, #p > 0.05

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