Fig. 3 | Cellular & Molecular Immunology

Fig. 3

From: A compromised specific humoral immune response against the SARS-CoV-2 receptor-binding domain is related to viral persistence and periodic shedding in the gastrointestinal tract

Fig. 3

Features of anti-RBD-specific IgM, IgA, and IgG. a Concentrations (cut-off index, COI) of anti-RBD-specific IgM (upper), IgA (middle), and IgG (bottom) antibodies at different time points. Times (weeks after symptom onset, W) are as marked. First, serum detection for each patient within 1 week after symptom onset was grouped separately as “1st detect.” Patient numbers at each timepoint are labeled separately for the positive retest group (red filled circle, positive retest.) and the negative retest group (black open circle, negative retest.). An unpaired t test with Welch’s correction was used. p Value: *p < 0.05, **p < 0.01, ***p < 0.001. b The speed of anti-RBD-specific antibody generation. Cumulative patient numbers (%) with anti-RBD IgM > 5 COI (upper), IgA > 5 COI (middle), and IgG > 10 (bottom) are shown. Positive retest group, red filled circle; negative retest group, black filled square. p Values (calculated by the log-rank (Mantel–Cox) test) are shown

Back to article page