Fig. 1 | Cellular & Molecular Immunology

Fig. 1

From: The interplay between dendritic cells and CD8 T lymphocytes is a crucial component of SARS-CoV-2 immunity

Fig. 1

A numeric reduction and impaired interaction of DCs and T lymphocytes characterizes an acute infection with SARS-CoV-2. DCs release less type I interferon and express fewer chemokines and costimulatory molecules. Subsequently, the generation and expansion of SARS-CoV-2-specific CD4 and CD8 T cells is delayed, and the release of Th1 cytokines is impaired, resulting in enhanced viral replication

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