Fig. 6
From: Generation of HIV-resistant cells with a single-domain antibody: implications for HIV-1 gene therapy
Selective survival of human CD4+ T cells expressing GPI-m36.4 during divergent HIV-1 infections. CEMss-CCR5 cells were transduced with GPI-m36.4/GFP and mixed with untransduced cells at a proportion of approximately 17% GFP-positive cells. The mixed population was challenged with 1,000 TCID50 of CXCR4-tropic NL4-3 (A) or CCR5-tropic THRO.c/2626 (B), and the proportion of transgene-expressing cells was monitored over time by flow cytometry. C Survival curves of transduced CEMss-CCR5 cells. Data from an experiment representative of three independent experiments are shown
