Table 2 Pleural, pericardial or peritoneal cavity effusions suspected to be related to MPTK-CAR-T cell infusion
From: Phase I study of CAR-T cells with PD-1 and TCR disruption in mesothelin-positive solid tumors
Type of event | ≤4 Wk After infusion (N = 15) | >4 Wk After infusion (N = 15) | ||
|---|---|---|---|---|
Grade < 3 | Grade ≥ 3 | Grade < 3 | Grade ≥ 3 | |
Number of patients (Percent) | ||||
Pleural effusion | 3 (20.0) | − | 1 (6.7) | 2 (13.3) |
Pericardial effusion | 1 (6.7) | − | 1 (6.7) | 1 (6.7) |
Ascites | 1 (6.7) | 2 (13.3) | − | − |
