Fig. 1 | Cellular & Molecular Immunology

Fig. 1

From: Screening HLA-A-restricted T cell epitopes of SARS-CoV-2 and the induction of CD8+ T cell responses in HLA-A transgenic mice

Fig. 1

Reference epitope peptides were tested in the DC-peptide-PBL coculture system. The HLA-A0201-restricted HCC1-1, HCC1-2, HCC5-3, HCC5-4, and HCC5-5 peptides and HLA-A2402-restricted HBV111 and HBV118 peptides were cocultured with DCs and PBLs from healthy donor PBMCs with matching HLA-A allotypes for 14 days. A The frequency of IFN-γ+ T cells in the CD3+/CD8+ T cell population for each reference epitope peptide and the no peptide negative control. B The percent proliferating CD8+ T cells in the CD3+/CD8+ T cell population for each reference epitope peptide and in the no peptide negative control

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