Fig. 3 | Cellular & Molecular Immunology

Fig. 3

From: Screening HLA-A-restricted T cell epitopes of SARS-CoV-2 and the induction of CD8+ T cell responses in HLA-A transgenic mice

Fig. 3

Candidate epitope peptides increased the percent of proliferating CD8+ T cells in DC-peptide-PBL cocultures. DCs were induced for 7 days from healthy donor PBMCs and then coincubated with candidate epitope peptides and autologous CFSE-prelabeled PBLs for 14 days. Cells were then harvested followed by flow cytometry analysis. The percent of proliferating CD8+ T cells in the CD3+/CD8+ T cell population for each positive epitope peptide and each responding donor was calculated according to the reduction in CFSE staining intensity and is presented as histograms

Back to article page