Fig. 5 | Cellular & Molecular Immunology

Fig. 5

From: Screening HLA-A-restricted T cell epitopes of SARS-CoV-2 and the induction of CD8+ T cell responses in HLA-A transgenic mice

Fig. 5

IFN-γ ELISPOT spot plots against the individual peptide pools in transgenic mice. Splenocytes from each primed transgenic mouse were harvested 7 days after the last booster and stimulated ex vivo with eight different peptide pools covering the 31 VEPs, AFP peptides (AFP158–166, AFP424–432) as irrelevant controls or without peptide as a negative control, followed by IFN-γ ELISPOT. Control group: N.S and PLGA-NPs; Vaccine A group: PLGA-NPs/peptides vaccines; Vaccine B group: R848/peptides vaccines; Vaccine C group: poly I: C/peptides vaccines

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