Fig. 4 | Cellular & Molecular Immunology

Fig. 4

From: Treatment with a JAK1/2 inhibitor ameliorates murine autoimmune cholangitis induced by IFN overexpression

Fig. 4

Ruxolitinib treatment decreased the frequencies of GC B cells and Tfh cells and led to lower serological AMA levels. A Flow cytometric analysis of splenic GC B and Tfh cells from mice treated with ruxolitinib (n = 11) or controls (n = 8) treated with carrier alone. B Levels of AMA before and at 4 and 8 weeks after ruxolitinib treatment in groups of ARE-Del+/− mice treated with ruxolitinib (n = 11) or mice treated with the control carrier (n = 11). *p < 0.05, **p < 0.01, ****p < 0.0001

Back to article page