Fig. 2 | Cellular & Molecular Immunology

Fig. 2

From: Immune regulatory networks coordinated by glycans and glycan-binding proteins in autoimmunity and infection

Fig. 2

Glycan-binding proteins: main localization and glycans recognition. C-type lectins (A) are expressed by a variety of cells and recognize a repertoire of sugar structures associated with either stimulatory or inhibitory responses. Galectins (B) are soluble GBPs, which can establish multivalent interactions with glycosylated receptors containing β-galactoside sugars on the surface of multiple cell types. Additionally, siglecs (C) are cell surface immune receptors capable of recognizing sialic acid structures

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