Fig. 4 | Cellular & Molecular Immunology

Fig. 4

From: Correlative CD4 and CD8 T-cell immunodominance in humans and mice: Implications for preclinical testing

Fig. 4

Relative dominance of HLA DRB1*01:01 and HLA DRB1*04:01 epitopes versus general HLA class II in SARS-CoV-2 S and N antigens. The response frequency of human nonspecific HLA class II (gray) and transgenic mouse HLA class II DRB1*01:01 (orange) and DRB1*04:01 (purple) epitopes for S (A, B) and N (C, D) SARS-CoV-2 antigens were calculated using the ImmunomeBrowser tool available at IEDB. Spearman’s correlations between mouse and human data are also shown for S (E, G) and N (F, H)

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