Fig. 6 | Cellular & Molecular Immunology

Fig. 6

From: Correlative CD4 and CD8 T-cell immunodominance in humans and mice: Implications for preclinical testing

Fig. 6

Differences in correlation coefficient (R) as a function of class I and class II restrictions. The R coefficient for each protein was obtained by comparing selected class I and class II human alleles or murine H2b haplotypes to the global human HLA of the corresponding class which is shown in Table 1. Differences in the distribution of values among the different groups were assessed using the Mann‒Whitney test. Each dot corresponds to the correlation coefficient of one viral antigen. Black dots: (A) A*02:01 (B) DRB1*01:01, gray dots: (A) B*07:02 (B) DRB1*04:01, white dots: (A, B) H-2b mouse haplotypes. *p < 0.05; **p < 0.01; ns not significant

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