Fig. 4
From: Mucosal T-cell responses to chronic viral infections: Implications for vaccine design
Possible approaches to enhancing the mucosal immunogenicity of replication-deficient CMV vectors. A schematic illustrating the approaches used to increase the immunogenicity of spread-deficient CMV vectors. All data were derived from nonmucosal vaccination routes. *Adenoviral minigene vectors induce inflationary CD8+ T-cell responses, but side-by-side comparisons with replication-deficient CMV vectors have not been performed
