Fig. 3: Electrical recording of cardiomyocyte activities using c-PEDOT:PSS/ITO-based transparent microelectrode arrays (c-PEDOT:PSS/ITO-MEAs).
From: High-performance, polymer-based direct cellular interfaces for electrical stimulation and recording
a A schematic pattern of a c-PEDOT:PSS/ITO-MEA with an optical micrograph of the recording electrode (inset). The scale bar denotes 50 μm. b A phase-contrast image of cardiomyocytes cultured on c-PEDOT:PSS/ITO-MEA. The electrode was false-colored for clarification, and the scale bar denotes 100 μm. c Bode plots of impedance on ITO-MEAs and c-PEDOT:PSS/ITO-MEAs. The active electrode exposed to the aqueous electrolyte is a circle with a diameter of 20 μm. d, e Recorded electrical potential trails of the cardiomyocytes on c-PEDOT:PET/ITO without and with 10 μM isoproterenol added. f, g Sorted action potentials from d and e, respectively. (N = 179 for control and N = 91 for 10 μM isoproterenol)
