Fig. 4: Concurrent electrical and optical Ca2+ recording of the cardiomyocyte activities on c-PEDOT:PSS/ITO-MEAs. | NPG Asia Materials

Fig. 4: Concurrent electrical and optical Ca2+ recording of the cardiomyocyte activities on c-PEDOT:PSS/ITO-MEAs.

From: High-performance, polymer-based direct cellular interfaces for electrical stimulation and recording

Fig. 4

a A schematic of the concurrent electrical recording and optical imaging of cellular activities. The electrical-field potential recording and optical Ca2+ dye fluorescence recording were performed using transparent c-PEDOT:PSS/ITO-MEAs and an EMCCD-equipped upright fluorescence microscope, respectively. b The trails of the action potentials (navy, top) and Ca2+ signals (black, bottom) from cardiomyocytes on c-PEDOT:PSS/ITO-MEAs simultaneously recorded by MEAs and EMCCD, respectively

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