Fig. 11: Simulation of NPs regulating the function of the membrane protein based on nano-bio interfaces. | NPG Asia Materials

Fig. 11: Simulation of NPs regulating the function of the membrane protein based on nano-bio interfaces.

From: Simulation of nanoparticles interacting with a cell membrane: probing the structural basis and potential biomedical application

Fig. 11

a Computer-simulated interaction between a hydrophobic NP of different surface charges and a pulmonary surfactant film under increasing compression (Å2/molecule). b PMF for interaction between the surfactant monolayer and the protein molecules. Reproduced with permission66. Copyright 2013, American Chemical Society. c Secreted inflammatory cytokine concentrations after the application of different integrin inhibitors or β8 siRNA interference. d Simulation of GO-PEG-membrane interactions from side-on and edge-on configurations. Reproduced with permission67. Copyright 2017, Springer Nature.

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