Fig. 7: Effect of NP hydrophobicity on the nano-bio interface interactions between NPs and the cell membrane. | NPG Asia Materials

Fig. 7: Effect of NP hydrophobicity on the nano-bio interface interactions between NPs and the cell membrane.

From: Simulation of nanoparticles interacting with a cell membrane: probing the structural basis and potential biomedical application

Fig. 7

a Structure of different NPs. The hydrophobic and hydrophilic beads are represented by yellow and magenta, respectively. b Final snapshot of each NP and skin lipid bilayer system at the end of a 6 μs unconstrained simulation. Reproduced with permission41. Copyright 2018, Royal Society of Chemistry. c Snapshots: lipid membranes interacting with 50 NPs at different values of hydrophobicity (H = 0, 0.5, 0.8, 1). d Free energy profiles as a function of the distance from the membrane center, in the presence of 50 NPs, and at different hydrophobicities, H. Reproduced with permission42. Copyright 2017, American Chemical Society.

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