Fig. 3 | Polymer Journal

Fig. 3

From: Stimuli-responsive hydrogels as a model of the dynamic cellular microenvironment

Fig. 3

a ABA triblock copolymer containing the pH-responsive poly(2-(isopropylamino)ethyl methacrylate) (PDPA) block and biocompatible zwitterionic poly(2-(methacryloyloxy)ethyl phosphorylcholine) (PMPC) block. Physical entanglement of flower micelles results in pH-responsive hydrogels. b Reversible switching of myoblast cells by the softening and stiffening of hydrogel substrates. Cells are contractile and spread on stiff substrates by gripping the substrates, but they take a round shape when the substrate elasticity is reduced from 40 kPa to 2 kPa

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