Fig. 3
From: Exploring metabolic adaptation of Streptococcus pneumoniae to antibiotics

Intracellular metabolites of (a) purine and pyrimidine metabolism, (b) carbon metabolism, and (c) amino acid metabolism of S. pneumoniae TIGR4Δcps. The illustrated heat maps with fold changes (FC) of metabolite concentrations under conditions of antibiotic treatment referred to control shows metabolites with increased concentrations compared with unstressed bacteria in yellow and with decreased concentrations in blue at the different time points (t15–t90). Gray fields: metabolites were not detected under stress and/or control conditions