Fig. 4

Extracellular metabolites of S. pneumoniae TIGR4Δcps. The illustrated heat map with fold changes (FC) of metabolite amounts after addition of antibiotics referred to control conditions both with normalization to optical density (600 nm) shows metabolites with higher concentrations compared to control in yellow and with lower concentrations in blue at the different time points (t₁₅–t₉₀). Gray fields: metabolites were not detected under stress and/or control conditions