Table 4 Antifungal activity of isavuconazole and comparator antifungal agents for non-Aspergillus mold isolates collected during 2011–2019 in Asia-Western Pacific medical centers participating in the SENTRY Antifungal Surveillance Program
Organism | MIC results in mg l−1a | ||
|---|---|---|---|
Isavuconazole | Posaconazole | Voriconazole | |
Fusarium solani species complex | >8 | >8 | >8 |
Fusarium solani species complex | >8 | >8 | 4 |
Fusarium solani species complex | >8 | >8 | 8 |
Fusarium solani species complex | NT | >8 | >8 |
Lichtheimia corymbifera | 2 | 0.5 | >8 |
Lichtheimia ramosa | NT | 1 | >8 |
Lichtheimia ramosa | NT | 0.5 | >8 |
Mucor circinelloides | NT | 2 | >8 |
Rhizomucor pusillus | NT | 0.5 | >8 |
Rhizopus microsporus group | 2 | 2 | >8 |
Rhizopus microsporus group | 2 | 0.5 | >8 |
Rhizopus oryzae SC | >8 | 1 | >8 |
Rhizopus oryzae SC | >8 | 2 | >8 |
Rhizopus oryzae SC | >8 | 4 | >8 |
Rhizopus oryzae SC | NT | 0.5 | >8 |
Cunninghamella sp. | 8 | 1 | >8 |
Syncephalastrum sp. | 2 | 0.5 | >8 |
Scedosporium apiospermum | NT | 1 | 1 |
Scedosporium apiospermum/S. boydii | NT | 1 | 0.12 |
Scedosporium apiospermum/S. boydii | NT | 0.5 | 0.5 |
Scedosporium apiospermum/S. boydii | 4 | 1 | 0.5 |
Scedosporium apiospermum/S. boydii | 4 | 2 | 0.5 |
Scedosporium apiospermum/S. boydii | 4 | 4 | 0.5 |
Scedosporium apiospermum/S. boydii | NT | 2 | 1 |
Scedosporium apiospermum/S. boydii | >8 | 2 | 1 |
Scedosporium apiospermum/S. boydii | 8 | 2 | 4 |
Scedosporium apiospermum/S. boydii | 1 | >8 | 8 |
Scedosporium aurantiacum | NT | 2 | 0.5 |
Scedosporium aurantiacum | NT | 2 | 0.5 |
Scedosporium aurantiacum | 8 | 2 | 0.5 |
Scedosporium aurantiacum | 8 | 2 | 0.5 |
Scedosporium aurantiacum | NT | 2 | 1 |
Scedosporium aurantiacum | NT | 2 | 1 |
Scedosporium aurantiacum | NT | 2 | 1 |
Exophiala dermatitidis | 1 | 0.25 | 0.25 |
Lomentospora prolificans | NT | >8 | 8 |
Lomentospora prolificans | NT | >8 | >8 |
Lomentospora prolificans | NT | >8 | >8 |
Lomentospora prolificans | NT | >8 | >8 |
Lomentospora prolificans | >8 | >8 | >8 |
Lomentospora prolificans | >8 | >8 | >8 |
Purpureocillium lilacinum | 0.5 | 0.5 | 0.25 |
Purpureocillium lilacinum | NT | >8 | 8 |
Pleurostoma richardsiae | 0.5 | 0.5 | 0.5 |
Rasamsonia argillacea | >8 | 2 | >8 |
Trichoderma longibrachiatum | NT | 2 | 0.5 |
Curvularia sp. | 0.5 | 0.25 | 0.5 |
Curvularia sp. | 1 | 0.5 | 0.5 |
Paecilomyces sp. | >8 | 0.25 | >8 |
Paecilomyces sp. | >8 | 0.25 | >8 |
Phaeoacremonium sp. | 2 | 0.5 | 0.5 |
Phialemoniopsis sp. | 0.5 | 0.25 | 0.25 |
Verruconis gallopava | 1 | 0.06 | 0.25 |
