Table 3 Primary and major secondary endpoints for glucose and insulin

iAUC0–2 (mmol × min/l)

117.2 ± 49.5

78.3 ± 41.8*

178.9 ± 71.4^†

135.9 ± 60.4^†*

iAUC2–3 (mmol × min/l)

1.7 ± 3.6

5.4 ± 7.4*

7.6 ± 9.7*

12.1 ± 15.3*

iAUC0–3 (mmol × min/l)

118.9 ± 49.6

83.7 ± 44.4*

186.5 ± 75.2^†

148.0 ± 67.2^†*

Peak rise (mmol/l)

2.97 ± 0.80

1.87 ± 0.60*

3.72 ± 0.89^†

2.72 ± 0.87^†*

Fasting (mmol/l)

4.62 ± 0.40

4.62 ± 0.42

5.18 ± 0.51

5.17 ± 0.48

2 h (mmol/l)

4.41 ± 0.45^‡

4.67 ± 0.40*

5.31 ± 0.80

5.44 ± 0.54^‡

2 h increment (mmol/l)

−0.21 ± 0.42

0.05 ± 0.36*

0.13 ± 0.68^†

0.27 ± 0.65^‡

Above:below fasting at 2 h

13:27

22:18^a

22:18^b

26:14

iAUC0–2 (pmol × h/l)

174.6 ± 120.7

117.6 ± 90.1*

302.3 ± 175.3^†

205.7 ± 113.9^†*

iAUC2–3 (pmol × h/l)

4.2 ± 7.3

8.1 ± 11.8

22.7 ± 32.8*

19.2 ± 21.6*

iAUC0–3 (pmol × h/l)

178.7 ± 123.0

125.7 ± 92.4*

325.0 ± 196.9^†

225.9 ± 129.8^†*

Peak rise (pmol/l)

278 ± 197

185 ± 146*

367 ± 180^†*

250 ± 139^†