Fig. 1: Model of mediation pathways of insulin sensitivity or insulin resistance on the association between vitamin D status and resting energy expenditure. | European Journal of Clinical Nutrition

Fig. 1: Model of mediation pathways of insulin sensitivity or insulin resistance on the association between vitamin D status and resting energy expenditure.

From: Hypothesized pathways for the association of vitamin D status and insulin sensitivity with resting energy expenditure: a cross sectional mediation analysis in Australian adults of European ancestry

Fig. 1

A1, A2, A3 are the indirect pathways from 25OHD to each IS/IR index, while the corresponding paths B1, B2 B3 links each IS/IR to REE. Ć is the direct pathway from 25OHD to REE. Total effect of a model is given by C = [Ć + (A x B)]. 25OHD, 25dihydroxycholecalciferol; McA McAuleys index; QUICKI Quantitative insulin insensitivity check index; TYG Triglyceride and glucose index; REE Resting energy expenditure.

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