Table 1 Baseline demographic and clinical characteristics of patients with Crohn’s disease and ulcerative colitis.

From: Body composition, physical activity, and quality of life in pediatric patients with inflammatory bowel disease on anti-TNF therapy—an observational follow-up study

Parameters

Crohn’s disease

Ulcerative colitis

p

Number of patients

21

11

p > 0.05

Age in years, mean+SD

15.2 ± 2.6

16.4 ± 2.2

p > 0.05

Gender, male % (n)

42% (9)

45% (51)

 

Median time between diagnosis and starting anti-TNF therapy(year) [IQR]

1.4 [3.6]

3.0 [3.3]

p > 0.05

PCDAI/PUCAI (mean ± SD)

23.1 ± 14.0

27.3 ± 23.0

 

CRP (mg/l, mean ± SD)

30.8 ± 43.8

14.1 ± 29.3

p > 0.05

Hemoglobin, g/dL, mean+SD

114.0 ± 19.8

129.6 ± 16.6

p = 0.03

Thrombocytes (G/L, mean ± SD)

451.0 ± 169.4

285.3 ± 120.9

p = 0.005

Albumin (g/L, mean+SD)

38.6 ± 5.8

42.4 ± 7.7

p > 0.05

Extent / Location of the disease

 L1

23.8% (5)

  

 L2

33.3% (7)

  

 L3

42.8% (9)

  

 L4

71.4% (15)

  

 E1

 

0

 

 E2

 

81.8% (9)

 

 E3

 

0

 

 E4

 

18.2% (2)

 

Disease Behavior (B1, B2, B3)

 B1

14

  

 B2

5

  

 B3

2

  

Medical treatment % (n)

 5-ASA

66% (14)

90 (10)

 

 AZA

80% (17)

63% (7)

 

 MTX

0

9% (1)

 

 Antibiotics

42% (9)

27% (3)

 

 Systemic corticosteroid

19% (4)

36% (4)

 

 Topical steroid

14% (3)

27/% (3)

 
  1. PCDAI Pediatric Crohn’s Disease Activity Index, PUCAI Pediatric Ulcerative Colitis Activity Index, CRP C-reactive protein, L1 Ileal, L2 Colonic, L3 Ileocolonic, L4 Upper gastrointestinal tract, B1 Non-stricturing, non-penetrating, B2 Stricturing, B3 Penetrating, E1 Ulcerative proctitis, E2 left-sided UC (distal UC), E3 extensive (hepatic flexure distally), E4 pancolitis (proximal to hepatic flexure), 5-ASA 5-aminosalicylic acid, AZA azathioprine, MTX methotrexate, SD standard deviation.