Fig. 1
From: KIF1A variants are a frequent cause of autosomal dominant hereditary spastic paraplegia
Schematic representation of the KIF1A protein with variants in dominant spastic paraplegia. Variants identified in this study are depicted above the schematic protein, isoform NP_004312.2, while previously described variants in autosomal dominant spastic paraplegia [11,12,13, 15, 29,30,31,32] are shown below the schematic. Protein domains are according to UniProt consortium (https://www.uniprot.org), with kinesin motor, cc coiled coil, FHA forkhead-associated, PH pleckstrin homology domains. aThis family has been described [15]
