Table 4 5-HTTLPR association p values obtained by VNTR.s for the first set of psychiatric phenotypes in GWAS atlas (https://atlas.ctglab.nl/).
Phenotype | p value |
---|---|
Alcohol intake frequency | 1.73E–06 |
Ever vs never smokers | 0.0002 |
Champagne/white wine intake | 0.003 |
Able to pay rent/mortgage as an adult | 0.009 |
Subjective well being | 0.009 |
Extraversion | 0.009 |
Ever vs never drinkers | 0.02 |
Frequency of inability to cease drinking in the last year | 0.02 |
Frequency of consuming six or more units of alcohol | 0.02 |
Frequency of feeling guilt or remorse after drinking alcohol in the last year | 0.04 |
Major depressive disorder, single episode | 0.06 |
Recent trouble relaxing | 0.06 |
Former vs current drinkers | 0.08 |
Current tobacco smoking | 0.08 |
Weight change during worst episode of depression | 0.1 |
Light smokers | 0.1 |
Former vs current smokers | 0.11 |
Depression possibly related to stressful or traumatic event | 0.12 |
Ever had period extreme irritability | 0.12 |
Recent worrying too much about different things | 0.13 |
Drinks per week | 0.17 |
Trouble falling or staying asleep, or sleeping too much | 0.2 |
Frequency of memory loss due to drinking alcohol in the last year | 0.2 |
Ever depressed for a whole week | 0.2 |
Reason for reducing amount of alcohol drunk: health precaution | 0.23 |
Thoughts of death during worst depression | 0.24 |
Felt loved as child | 0.25 |
Frequency of unenthusiasm/disinterest in last 2 weeks | 0.26 |
Frequency of tiredness/lethargy in last 2 weeks | 0.28 |
Someone to take to doctor when needed as a child | 0.28 |
Fraction of day affected during worst episode of depression | 0.29 |
Frequency of depressed days during worst episode of depression | 0.29 |
Been in serious accident believed to be life-threatening | 0.29 |
Ever worried more than most people would in similar situation | 0.29 |
Recent restlessness | 0.3 |
Why stopped smoking: financial reasons | 0.3 |
Been in a confiding relationship as an adult | 0.31 |
Ever had prolonged feelings of sadness or depression | 0.31 |