Table 4 5-HTTLPR association p values obtained by VNTR.s for the first set of psychiatric phenotypes in GWAS atlas (https://atlas.ctglab.nl/).

From: A summary-statistics-based approach to examine the role of serotonin transporter promoter tandem repeat polymorphism in psychiatric phenotypes

Phenotype

p value

Alcohol intake frequency

1.73E–06

Ever vs never smokers

0.0002

Champagne/white wine intake

0.003

Able to pay rent/mortgage as an adult

0.009

Subjective well being

0.009

Extraversion

0.009

Ever vs never drinkers

0.02

Frequency of inability to cease drinking in the last year

0.02

Frequency of consuming six or more units of alcohol

0.02

Frequency of feeling guilt or remorse after drinking alcohol in the last year

0.04

Major depressive disorder, single episode

0.06

Recent trouble relaxing

0.06

Former vs current drinkers

0.08

Current tobacco smoking

0.08

Weight change during worst episode of depression

0.1

Light smokers

0.1

Former vs current smokers

0.11

Depression possibly related to stressful or traumatic event

0.12

Ever had period extreme irritability

0.12

Recent worrying too much about different things

0.13

Drinks per week

0.17

Trouble falling or staying asleep, or sleeping too much

0.2

Frequency of memory loss due to drinking alcohol in the last year

0.2

Ever depressed for a whole week

0.2

Reason for reducing amount of alcohol drunk: health precaution

0.23

Thoughts of death during worst depression

0.24

Felt loved as child

0.25

Frequency of unenthusiasm/disinterest in last 2 weeks

0.26

Frequency of tiredness/lethargy in last 2 weeks

0.28

Someone to take to doctor when needed as a child

0.28

Fraction of day affected during worst episode of depression

0.29

Frequency of depressed days during worst episode of depression

0.29

Been in serious accident believed to be life-threatening

0.29

Ever worried more than most people would in similar situation

0.29

Recent restlessness

0.3

Why stopped smoking: financial reasons

0.3

Been in a confiding relationship as an adult

0.31

Ever had prolonged feelings of sadness or depression

0.31