Table 5 5-HTTLPR association results obtained by VNTR.s for some cognitive and neurological phenotypes in GWAS atlas (https://atlas.ctglab.nl/).

From: A summary-statistics-based approach to examine the role of serotonin transporter promoter tandem repeat polymorphism in psychiatric phenotypes

Phenotype

Phenotypes class

p value

Intelligence

Cognitive

5.10E–08

Pairs matching test—number of incorrect matches in round

Cognitive

0.04

Pairs matching test—time to complete round

Cognitive

0.13

Handedness

Cognitive

0.14

Trail making test—duration to complete numeric path (trail #1)

Cognitive

0.16

Symbol digit substitution test—duration to entering value

Cognitive

0.44

Reaction time

Cognitive

0.46

Fluid intelligence test—number of fluid intelligence questions attempted within time limit

Cognitive

0.55

 Numeric memory test—maximum digits remembered correctly

Cognitive

0.61

 Trail making test—duration to complete alphanumeric path (trail #2)

Cognitive

0.68

 Symbol digit substitution test—number of symbol digit matches made correctly

Cognitive

0.82

 Symbol digit substitution test—number of symbol digit matches attempted

Cognitive

0.92

 Headache

Neurological

0.02

 Knee pain

Neurological

0.03

 Back pain for 3+ months

Neurological

0.03

 Neck or shoulder pain

Neurological

0.06

 Hip pain

Neurological

0.3

 Migraine

Neurological

0.37

 Alzheimer disease

Neurological

0.55

 Headaches for 3+ months

Neurological

0.56

 Knee pain for 3+ months

Neurological

0.83

 Neck/shoulder pain for 3+ months

Neurological

0.88

 Stomach or abdominal pain

Neurological

1

 Back pain

Neurological

1