Fig. 1: Filtering approach and cohort characteristics. | European Journal of Human Genetics

Fig. 1: Filtering approach and cohort characteristics.

From: Prevalence of hereditary tubulointerstitial kidney diseases in the German Chronic Kidney Disease study

Fig. 1

A Workflow used to filter individuals from the GCKD and subsequent quality control steps to ensure DNA integrity and sample identity. Clinical category based filtering resulted in 326 entries which corresponded to 303 unique individuals (5.8% of the whole GCKD cohort). Of these 271 (89.4%) passed all quality control steps and were included in the final analyses. B Upset plot showing the distribution and overlap of the nine clinical criteria used to filter the study cohort from the GCKD cohort. C Age distribution by sex in the final cohort. The y-axis depicts age classes 5-year intervals. The x-axis shows the number of individuals, with females on the right (red) and males on the left (blue) side. Age is reported at inclusion into the GCKD study. D Distribution of different kidney function parameters at GCKD study inclusion: Top (dark gray) eGFR by CKD-EPI, Middle (blue) eGFR by MDRD, Bottom (light gray) Albumin-Creatinine Ratio (ACR).

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