Table 1 Respondent characteristics n = 474, compared to the general obstetric population.

	N (%)	General Dutch obstetric population (%)
Age (years) (Q1) (missing 1)
≤29	111 (23.5)	(33.5)^a
30–34	238 (50.3)	(40.8)^a
≥35	124 (26.2)	(25.7)^a
Education level (missing 1)^b
Low	16 (3.4)	(12.3)^a
Intermediate	120 (25.3)	(35.4)^a
High	337 (71.2)	(50.9)^a
Country of origin (missing 2)^c
Dutch	410 (86.9)	(67.0)^a
Other-Western	39 (8.3)	(11.4)^a
Non-Western	23 (4.9)	(21.6)^a
Religious affiliation (missing 6)
Non-religious	327 (69.9)	~(63)^a
Religious	141 (30.1)	~(37)^a
Parity (missing 2)
Primiparous	234 (49.5)	(45.4)^a
Multiparous	239 (50.5)	(55.6)^a
Health literacy (missing 2)^d
Adequate	414 (87.7)
Inadequate	58 (12.3)
Gestational age (Q1) (weeks) (missing 2)
≤10	162 (34.3)
11–14	299 (63.3)
≥15	11 (2.3)
Informed choice for having NIPT (missing 103)^e
Informed choice	288 (77.6)
Uninformed choice	83 (22.4)
Choice for NIPT analysis (Q2) (missing 1)
Genome-wide NIPT	362 (76.5)	(77.6)^f
Targeted NIPT	103 (21.8)	(23.4)^f
Do not recall	8 (1.7)
NIPT result (Q2) (missing 3)
Low-risk	465 (98.7)	(97.7)^f
High-risk: trisomies 21,18,13	4 (0.9)	(0.46)^f
High-risk: finding other than trisomies 21,18, or 13	2 (0.4)	(0.36)^f

NIPT non-invasive prenatal test, Q questionnaire, pre- (Q1) or post-test (Q2).
^aSource: Statistics Netherlands. Maternal age, country of origin and parity of all livebirths in the Netherlands in 2019. Education level of women in the Netherlands aged 25–45 years in 2019. Religious affiliation of women in the Netherlands aged 25–35 years in 2018.
^bEducation levels were categorized as low: elementary school, low level secondary school or lower vocational training; intermediate: high level secondary school or intermediate vocational training; or high: high vocational training or university.
^cCountry of origin was categorized as Dutch (according to Statistics Netherlands) if both parents were born in the Netherlands; other Western: one or both parents were born in Europe (excluding Turkey), North America, Oceania, Indonesia or Japan; non-Western: one or both parents were born in Africa, Latin-America, Asia (excluding Indonesia or Japan) or Turkey. Maternal country of birth was leading if both parents were born abroad.
^dHealth literacy was measured using the three-item set of brief screening questions [24]. Categorized as inadequate if answered anything other than ‘never’ or ‘occasionally’ on one or more questions.
^eBased on van der Meij et al. 2022 [21]. Women with a neutral attitude (n = 103) were excluded from the calculation of informed choice.
^fBased on van der Meij et al. 2019 [5].

Search