Table 1 Demographics of proband and relative populations among studies that reported demographic information.

Bednar 2020

Non-Hispanic White: 140 (93.3%)

Not reported

Black: 2 (1.3%)

Asian: 2 (1.3%)

Native American/Alaska Native: 2 (1.3%)

Other: 4 (2.7%)

Biesecker 2000

Not reported

Non-Hispanic White: 172 (100%)

Caswell-Jin 2019

Non-Hispanic White: 697 (85.6%)

Non-Hispanic White: 899 (86.0%)

Hispanic: 36 (4.4%)

Hispanic: 69 (6.6%)

Black: 4 (0.5%)

Black: 5 (0.5%)

Asian: 35 (4.3%)

Asian: 34 (3.3%)

Native American: 1 (0.1%)

Multiple: 38 (3.6%)

Multiple: 41 (5.0%)

Courtney 2019

Asian: 175 (95.6%)

Asian: 106 (94.6%)

Other: 8 (4.4%)

Other: 6 (5.4%)

Dilzell 2014

Non-Hispanic White: 41 (91.1%)

Non-Hispanic White: 20 (90.9%)

Native American: 2 (4.4%)

Hispanic: 1 (4.5%)

Black: 1 (2.2%)

Native American: 1 (4.5%)

Asian: 1 (2.2%)

Fehniger 2013

Non-Hispanic White: 32 (43.8%)

Non-Hispanic White: 135 (30.5%)

Hispanic: 17 (23.3%)

Hispanic: 123 (27.8%)

Asian: 14 (19.2%)

Asian: 117 (26.4%)

Black: 7 (9.6%)

Black: 53 (12.0%)

Multiple: 3 (4.1%)

Multiple: 15 (3.4%)

Finlay 2008

Non-Hispanic White: 114 (99.1%)

Not reported

Other: 1 (0.9%)

Griffin 2020

Non-Hispanic White: 62 (96.9%)

Not reported

Black: 2 (3.1%)

Hadley 2003

Non-Hispanic White: 87 (87.0%)

Not reported

Black: 7 (7.0%)

Hispanic: 3 (3.0%)

Asian: 2 (2.0%)

Native American: 1 (1.0%)

Lerman 1996

Not reported

Non-Hispanic White: 192 (100%)

Lerman 1999

Not reported

Non-Hispanic White: 138 (99.3%)

Native American: 1 (0.7%)

Lieberman 2018

Non-Hispanic White: 148 (100%)

Not reported

McGivern 2004

Non-Hispanic White: 37 (97.4%)

Not reported

Native American: 1 (2.6%)

Petersen 2018

Non-Hispanic White: 30 (93.8%)

Non-Hispanic White: 90 (94.7%)

Other: 2 (6.3%)

Other: 5 (5.3%)

Yoon 2011

Asian: 37 (100%)

Asian: 61 (100%)