Fig. 5: Tree and leaf visualization of Euclidean clustering of all 57 cohorts using the top n DMPs for each group, where n = min (# of DMPs, 500).

Cohort samples were aggregated using the median value of each probe within a group. A leaf node represents a cohort, with node sizes illustrating relative scales of the number of selected DMPs for the corresponding cohort, and node colors are indicative of the global mean methylation difference.