Table 1 Overview of 515 CAKUT cases referred to a diagnostic laboratory for cES.

From: Clinical exome sequencing efficacy and phenotypic expansions involving non-isolated congenital anomalies of kidney and urinary tract (CAKUT+)

Ā 

Definitive

Probable

Provisional

Unsolved

Significance (P < 0.05)

Total (%)

94 (18.3)

47 (9.1)

62 (12.0)

312 (60.6)

Ā 

Mean age (SD)

5.1 (5.7)

7.7 (10.6)

4.0 (4.9)

5.3 (7.3)

NS

Age Group (%)

Ā Ā Ā Ā 

NS

Prenatal

5 (11.4)

1 (2.3)

8 (18.2)

30 (68.2)

Ā 

Neonatal (<1 mo)

8 (16.3)

1 (2.0)

7 (14.3)

33 (67.3)

Ā 

Infant (1 mo–1 yr)

16 (16.0)

8 (8.0)

10 (10.0)

66 (66.0)

Ā 

Toddler (1–2 yr)

9 (17.6)

7 (13.7)

8 (15.7)

27 (52.9)

Ā 

Childhood (2–11 yr)

40 (22.1)

21 (11.6)

23 (12.7)

97 (53.6)

Ā 

Adolescent (11–21 yr)

13 (18.6)

6 (8.6)

6 (8.6)

45 (64.3)

Ā 

Adulthood (21+ yr)

2 (10.5)

3 (15.8)

0 (0.0)

14 (73.7)

Ā 

Unknown

1 (100.0)

0 (0.0)

0 (0.0)

0 (0.0)

Ā 

Sex (%)

Ā Ā Ā Ā 

NS

Female

39 (18.3)

20 (9.4)

30 (14.1)

124 (58.2)

Ā 

Male

51 (19.6)

26 (10)

24 (9.2)

159 (61.2)

Ā 

Unknown (Fetal)

4 (9.5)

1 (2.4)

8 (19.0)

29 (69.0)

Ā 
  1. SD = Standard deviation, NS = Not significant, mo = months, yr = years.