Table 2 Details of the study design and population of involved trials.
Study | Study design | Participants (M/ F) | Average age (range in years) | Teeth restored | Follow-up |
|---|---|---|---|---|---|
Salem et al., 202236 | RCT double-blind, parallel | 36 (9/27) | 31 ± 7.6 years | 36 | 1 year |
Endo Hoshino et al., 202234 | RCT double-blind, split mouth | 53 | 48.3 years (±10.0) | 159 | 4 years |
Sekundo et al., 202237 | RCT double-blind, split mouth | 60 (31/29) | (≥18) | 120 | 3 years |
Hardan et al., 20216 | RCT split mouth | 30 (12/18) | 25.8 ± 7.49 (18–45) | 60 | 1 year |
Durão et al., 202132 | RCT double-blind, split mouth | 46 (22/24) | 14.82 (12–18) | 138 | 3 years |
Balkaya & Arslan, 202038 | RCT double-blind, split mouth | 54 (23/31) | 22 (20–32) | 109 | 2 years |
Frascino et al., 202033 | RCT double-blind, split mouth | 53 | 48.3 ± 10 | 159 | 1 year |
Al-Sheikh, 201935 | RCT split mouth | 40 | (20–40) | 80 | 6 months |
Heck et al., 201839 | RCT split mouth | 46 | (≥18) | 96 | 10 years |
Atabek et al., 201740 | RCT split mouth | 30 | (7–16) | 60 | 2 years |
Bayraktar et al., 201741 | RCT split mouth | 50 | 25.8 ± 7.49 (18–45) | 200 | 1 year |
Colak et al., 201742 | RCT double-blind, split mouth | 34 (24/10) | 33.74 ± 6.8 (23–56) | 74 | 1 year |
Karaman et al., 201743 | RCT double-blind, split mouth | 37 (16/21) | 27 (19–41) | 94 | 3 years |
Van Dijken & Pallesen, 201744 | RCT double-blind, split mouth | 38 (22/16) | 55.3 (32–87) | 106 | 6 years |
Yazici et al., 201745 | RCT double-blind, split mouth | 50 (24/26) | (24–55) | 104 | 3 years |
Alkurdi & Abboud, 201646 | RCT parallel | 60 | (20–50) | 60 | 1 year |
Van Dijken & Pallesen, 201647 | RCT double-blind, split mouth | 86 (44/42) | 52.4 (20–86) | 200 | 5 years |
Manhart et al., 201048 | RCT split mouth | 43 | 44.3 (19–67) | 96 | 4 years |
