Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Article
  • Published:

Emerging trends in the early diagnosis of dental caries: a scoping review of artificial intelligence, digital diagnostics, and teledentistry

Abstract

Background

Dental caries is the most prevalent chronic, noncommunicable condition affecting individuals of all ages and socio-economic status. The recent technological advancements in artificial intelligence (AI), digital diagnostics, and teledentistry have been genuinely promising in revolutionizing the future of early caries detection and preventive care. However, an integrated understanding of these advancements and their clinical readiness remains limited.

Aim

To systematically map and synthesize the current evidence on the use of AI, digital diagnostic technologies, and teledentistry for the early diagnosis in dental caries.

Method

This scoping review followed the Arksey and O’Malley framework and adhered to PRISMA-ScR guidelines. Studies published between 1997 and 2025 were identified through PubMed, Scopus, Web of Science, and manual searches. Articles with AI, digital diagnostic tools, or teledentistry for caries detection were selected, with a specific focus on early caries detection. Data extraction was performed using a standardized charting form and narration across three topics: AI-assisted diagnostics, digital tools, and remote detection through teledentistry.

Results

Thirty studies were considered after screening and evaluation of eligibility as they met the selection criteria out of 1000 initial records. The studies included retrospective (n = 10), prospective (n = 7), diagnostic accuracy (n = 6), in-vitro (n = 5), and feasibility studies (n = 2). AI-supported studies showed excellent diagnostic accuracy ranging from well over 90% for the more performing AI to sensitivity and specificity values of 80–95%. However, digital methods, including near-infrared light transillumination, laser fluorescence, photothermal imaging, and ultrasonic technology yielded mixed but positive results in early lesion identification.

Conclusion

This scoping review highlights the increasing role of AI, digital diagnostics, and teledentistry in the early detection of dental caries. These technologies augment diagnostic precision, improve preventive care, and provide greater access, particularly for underserved areas. However, regarding real-world validation, standardization and ethical integration remain challenges. Future work needed in clinical trials, data quality, and regulatory harmonization to support safe, effective, and equitable implementation in dental practice.

This is a preview of subscription content, access via your institution

Access options

Buy this article

USD 39.95

Prices may be subject to local taxes which are calculated during checkout

Fig. 1
Fig. 2

Similar content being viewed by others

Data availability

All the data are included in the current article.

References

  1. Pitts NB. Dental caries. Nat Rev Dis Prim. 2017;3:1–16.

    Google Scholar 

  2. Gowdar IM, BinKhames YM, Althani RA, Almuthaybiri SM, Alabdulmuhsin SB, Alatiyyah FM. Knowledge of caries risk assessment among dental students in Riyadh Region Saudi Arabia. J Pharm Bioallied Sci. 2022;14:S327–S330.

    Article  PubMed  PubMed Central  Google Scholar 

  3. Abesi F, Mirshekar A, Moudi E, Seyedmajidi M, Haghanifar S, Haghighat N, et al. Diagnostic accuracy of digital and conventional radiography in the detection of non-cavitated approximal dental caries. Iran J Radiol. 2012;9:17–21.

    Article  PubMed  PubMed Central  Google Scholar 

  4. Dove SB. Radiographic diagnosis of dental caries. J Dent Educ. 2001;65:985–90.

    Article  CAS  PubMed  Google Scholar 

  5. Lee JH, Kim DH, Jeong SN, Choi SH. Detection and diagnosis of dental caries using a deep learning-based convolutional neural network algorithm. J Dent. 2018;77:106–11.

    Article  PubMed  Google Scholar 

  6. Schwendicke F, Rossi JG, Göstemeyer G, Elhennawy K, Cantu AG, Gaudin R, et al. Cost-effectiveness of artificial intelligence for proximal caries detection. J Dent Res. 2021;100:369–76.

    Article  CAS  PubMed  Google Scholar 

  7. Musri N, Christie B, Ichwan S, Cahyanto A. Deep learning convolutional neural network algorithms for the early detection and diagnosis of dental caries on periapical radiographs: a systematic review. Imaging Sci Dent. 2021;51:237–242.

    Article  PubMed  PubMed Central  Google Scholar 

  8. Devlin H, Williams T, Graham J, Ashley M. The ADEPT study: a comparative study of dentists’ ability to detect enamel-only proximal caries in bitewing radiographs with and without the use of AssistDent artificial intelligence software. Br Dent J. 2021;231:481–5.

    Article  PubMed  PubMed Central  Google Scholar 

  9. Al Jallad N, Ly-Mapes O, Hao P, Ruan J, Ramesh A, Luo J, et al. Artificial intelligence-powered smartphone application, AICaries, improves at-home dental caries screening in children: Moderated and unmoderated usability test. PLOS Digital health. 2022;1:e0000046.

    Article  PubMed  PubMed Central  Google Scholar 

  10. Panyarak W, Wantanajittikul K, Charuakkra A, Prapayasatok S, Suttapak W. Enhancing caries detection in bitewing radiographs using YOLOv7. J Digital Imaging. 2023;36:2635–47.

    Article  Google Scholar 

  11. Güneç, H.G., Success of Caries and Periapical Infection Diagnoses on Panoramic images: Artificial Intelligence vsJunior and Specialist Dentists. 2023.

  12. Ibrahim SH, Nabil R, Edward P. Diagnostic accuracy of digital radiography and novel diagnostic tools versus visual ICDAS criteria: A systematic review. Mathews J Dent. 2021;5:1–20.

    CAS  Google Scholar 

  13. Beltrán JA, Manco RAL, Guerrero ME. Comparison of the diagnostic accuracy of cone beam computed tomography and three intraoral radiographic systems in the diagnosis of carious lesions in vitro. J Oral Res. 2020;9:466–73.

    Article  Google Scholar 

  14. Abogazalah N, Eckert GJ, Ando M. In vitro performance of near infrared light transillumination at 780-nm and digital radiography for detection of non-cavitated approximal caries. J Dent. 2017;63:44–50.

    Article  CAS  PubMed  Google Scholar 

  15. Abdelaziz M. Detection, diagnosis, and monitoring of early caries: the future of individualized dental care. Diagnostics. 2023;13:3649.

    Article  PubMed  PubMed Central  Google Scholar 

  16. Jeon RJ, Matvienko A, Mandelis A, Abrams SH, Amaechi BT, Kulkarni G. Detection of interproximal demineralized lesions on human teeth in vitro using frequency-domain infrared photothermal radiometry and modulated luminescence. J Biomed Opt. 2007;12:034028–034028-13.

    Article  PubMed  Google Scholar 

  17. Qi X. Discrimination of tooth composition through temporally shaped femtosecond laser-induced breakdown spectroscopy. J Laser Appl. 2023;35:022010.

  18. Wang, T.-A. Early detection of caries with ultrahigh-resolution optical coherence tomography (Conference Presentation). in Label-free Biomedical Imaging and Sensing (LBIS) 2023. 2023. SPIE.

  19. Group, C.O.H., Transillumination and optical coherence tomography for the detection and diagnosis of enamel caries. Cochrane Database Syst Rev. 1996. 2021.

  20. Wang F, Liu J, Yang J, Oliullah M, Wang X, Wang Y. High-frequency heterodyne lock-in thermography (HeLIT): a highly sensitive method to detect early caries. Appl Phys Lett. 2016;109:141904.

  21. Ojaghi A, Tabatabaei N. Detection of early occlusal and proximal dental caries using long-wavelength infrared thermophotonic lock-in imaging. in 2016 Photonics North (PN). 2016. IEEE.

  22. Golsanamloo O, Iranizadeh S, Jamei Khosroshahi AR, Erfanparast L, Vafaei A, Ahmadinia Y, et al. Accuracy of teledentistry for diagnosis and treatment planning of pediatric patients during COVID-19 pandemic. Int J Telemed Appl. 2022;2022:4147720.

    PubMed  PubMed Central  Google Scholar 

  23. ADA. Caries Risk Assessment and Management. 2023 20/02/2025]; Available from: https://www.ada.org/resources/ada-library/oral-health-topics/caries-risk-assessment-and-management?_gl=1*cuhrpq*_ga*MTQ3NzAxNjU5Ni4xNzQ2MDg1ODgx*_ga_X8X57NRJ4D*MTc0NjA4NTg3OS4xLjEuMTc0NjA4NTkyMi4wLjAuMA..*_gcl_au*MjExMzE5MTA0OC4xNzQ2MDg1ODgz*_ga_NVSBFQCBYE*MTc0NjA4NTg3OS4xLjEuMTc0NjA4NTkyNC4xNS4wLjA.*_ga_JDE0LTHGWL*MTc0NjA4NTg3OS4xLjEuMTc0NjA4NTk4NC41MC4wLjA.

  24. AlShaya MS, Assery MK, Pani SC. Reliability of mobile phone teledentistry in dental diagnosis and treatment planning in mixed dentition. J Telemed Telecare. 2020;26:45–52.

    Article  PubMed  Google Scholar 

  25. Jobin A, Ienca M, Vayena E. The global landscape of AI ethics guidelines. Nat Mach Intell. 2019;1:389–99.

    Article  Google Scholar 

  26. Ongena YP, Haan M, Yakar D, Kwee TC. Patients’ views on the implementation of artificial intelligence in radiology: development and validation of a standardized questionnaire. Eur Radiol. 2020;30:1033–40.

    Article  PubMed  Google Scholar 

  27. Ünsal G, Orhan K. Future Perspectives of Artificial Intelligence in Dentistry, in Artificial Intelligence in Dentistry. 2024, Springer. p. 353-64.

  28. R. AbdELkader A, Hafez Ibrahim S, Elsayed Hassanein O. Reliability of impedance spectroscopy versus digital radiograph and ICDAS-II in occlusal caries detection: a prospective clinical trial. Sci Rep. 2024;14:16553.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  29. Chan EK, Wah YY, Lam WY, Chu CH, Yu OY. Use of digital diagnostic aids for initial caries detection: a review. Dent J. 2023;11:232.

    Article  Google Scholar 

  30. Akhter MN. Using technological diagnostic tools to find early caries: a systematic review. Dinkum J Med Innov. 2023;2:271–83.

    Google Scholar 

  31. Esmaeilyfard R, Bonyadifard H, Paknahad M. Dental caries detection and classification in CBCT images using deep learning. Int Dent J. 2024;74:328–34.

    Article  PubMed  Google Scholar 

  32. Kühnisch J, Meyer O, Hesenius M, Hickel R, Gruhn V. Caries detection on intraoral images using artificial intelligence. J Dent Res. 2022;101:158–65.

    Article  PubMed  Google Scholar 

  33. Mertens S, Krois J, Cantu AG, Arsiwala LT, Schwendicke F. Artificial intelligence for caries detection: randomized trial. J Dent. 2021;115:103849.

    Article  PubMed  Google Scholar 

  34. Ayan E, Bayraktar Y, Çelik Ç, Ayhan B. Dental student application of artificial intelligence technology in detecting proximal caries lesions. J Dent Educ. 2024;88:490–500.

    Article  PubMed  Google Scholar 

  35. Luke AM, Rezallah NNF. Accuracy of artificial intelligence in caries detection: a systematic review and meta-analysis. Head Face Med. 2025;21:24.

    Article  PubMed  PubMed Central  Google Scholar 

  36. Oztekin F, Katar O, Sadak F, Yildirim M, Cakar H, Aydogan M, et al. An explainable deep learning model to prediction dental caries using panoramic radiograph images. Diagnostics. 2023;13:226.

    Article  PubMed  PubMed Central  Google Scholar 

  37. Elhennawy K, Askar H, Jost-Brinkmann PG, Reda S, Al-Abdi A, Paris S, et al. In vitro performance of the DIAGNOcam for detecting proximal carious lesions adjacent to composite restorations. J Dent. 2018;72:39–43.

    Article  PubMed  Google Scholar 

  38. Diniz MB, Boldieri T, Rodrigues JA, Santos-Pinto L, Lussi A, Cordeiro RC. The performance of conventional and fluorescence-based methods for occlusal caries detection: an in vivo study with histologic validation. J Am Dent Assoc. 2012;143:339–50.

    Article  PubMed  Google Scholar 

  39. Mortensen D, Dannemand K, Twetman S, Keller MK. Detection of non-cavitated occlusal caries with impedance spectroscopy and laser fluorescence: an in vitro study. open Dent J. 2014;8:28–32.

    Article  PubMed  PubMed Central  Google Scholar 

  40. Gomez J. Detection and diagnosis of the early caries lesion. BMC oral health. 2015;15:S3.

    Article  PubMed  PubMed Central  Google Scholar 

  41. Mohanraj M, Prabhu VR, Senthil R. Diagnostic methods for early detection of dental caries-A review. Int J Pedod Rehabil. 2016;1:29–36.

    Google Scholar 

  42. Naganuma Y, Hatori K, Iikubo M, Takahashi M, Hagiwara Y, Kobayashi K, et al. Application of scanning acoustic microscopy for detection of dental caries lesion. Open J Stomatol. 2023;13:12–24.

    Article  Google Scholar 

  43. da Silva EJ, de Miranda EM, Mota C, Das A, Gomes A. Photoacoustic imaging of occlusal incipient caries in the visible and near-infrared range. Imaging Sci Dent. 2021;51:107–115.

    Article  PubMed  PubMed Central  Google Scholar 

  44. Ntovas P, Michou S, Benetti AR, Bakhshandeh A, Ekstrand K, Rahiotis C, et al. Occlusal caries detection on 3D models obtained with an intraoral scanner. A validation study. J Dent. 2023;131:104457.

    Article  CAS  PubMed  Google Scholar 

  45. Estai M, Kanagasingam Y, Huang B, Checker H, Steele L, Kruger E, et al. The efficacy of remote screening for dental caries by mid-level dental providers using a mobile teledentistry model. Community Dent Oral Epidemiol. 2016;44:435–41.

    Article  PubMed  Google Scholar 

  46. Estai M, Kanagasingam Y, Huang B, Shiikha J, Kruger E, Bunt S, et al. Comparison of a smartphone-based photographic method with face-to-face caries assessment: a mobile teledentistry model. Telemed e-Health. 2017;23:435–40.

    Article  Google Scholar 

  47. AlShaya M, Farsi D, Farsi N, Farsi N. The accuracy of teledentistry in caries detection in children–A diagnostic study. Digital health. 2022;8:20552076221109075.

    Article  PubMed  PubMed Central  Google Scholar 

  48. Kargozar S, Jadidfard M-P. Teledentistry accuracy for caries diagnosis: a systematic review of in-vivo studies using extra-oral photography methods. BMC Oral Health. 2024;24:828.

    Article  PubMed  PubMed Central  Google Scholar 

  49. Lamas-Lara VF, Mattos-Vela MA, Evaristo-Chiyong TA, Guerrero ME, Jiménez-Yano JF, Gómez-Meza DN. Validity and reliability of a smartphone-based photographic method for detection of dental caries in adults for use in teledentistry. Front Oral Health. 2025;6:1470706.

    Article  PubMed  PubMed Central  Google Scholar 

  50. Price MD, Ureles SD, Alhazmi H, Sulyanto RM, Ng MW. Diagnostic accuracy of detecting caries and other intraoral findings using parent-obtained smartphone photographs in teledentistry. J Am Dent Assoc. 2025;156:601–10.e1.

  51. Sakr L, Abbas H, Thabet N, Abdelgawad F. Reliability of teledentistry mobile photos versus conventional clinical examination for dental caries diagnosis on occlusal surfaces in a group of school children: a diagnostic accuracy study. BMC Oral Health. 2025;25:545.

    Article  PubMed  PubMed Central  Google Scholar 

  52. Aly NM, El Kashlan MK, Giraudeau N, El Tantawi M. Comparison of Intraoral Cameras and Smartphones in Early Childhood Caries Detection: A Diagnostic Accuracy Study. J Evid-Based Dent Pract. 2024;24:102041.

    Article  PubMed  Google Scholar 

  53. Abdat M, Herwanda MJ, Soraya C. Detection of caries and determination of treatment needs using DentMA teledentistry: A deep learning approach. Maj Kedokt Gigi. 2024;57:62–67.

    Google Scholar 

  54. Zhang J-W, Fan J, Zhao FB, Ma B, Shen XQ, Geng YM. Diagnostic accuracy of artificial intelligence-assisted caries detection: a clinical evaluation. BMC Oral Health. 2024;24:1095.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  55. Lian L, Zhu T, Zhu F, Zhu H. Deep learning for caries detection and classification. Diagnostics. 2021;11:1672.

    Article  PubMed  PubMed Central  Google Scholar 

  56. Geetha V, Aprameya K, Hinduja DM. Dental caries diagnosis in digital radiographs using back-propagation neural network. Health Inf Sci Syst. 2020;8:1–14.

    Article  Google Scholar 

  57. Bayrakdar IS, Orhan K, Akarsu S, Çelik Ö, Atasoy S, Pekince A, et al. Deep-learning approach for caries detection and segmentation on dental bitewing radiographs. Oral Radiol. 2022;38:1–12.

    Article  Google Scholar 

  58. Chen X, Guo J, Ye J, Zhang M, Liang Y. Detection of proximal caries lesions on bitewing radiographs using deep learning method. Caries Res. 2022;56:455–63.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  59. Ahrari F, Akbari M, Mohammadi M, Fallahrastegar A, Najafi MN. The validity of laser fluorescence (LF) and near-infrared reflection (NIRR) in detecting early proximal cavities. Clin Oral Investig. 2021;25:4817–24.

    Article  PubMed  Google Scholar 

  60. Matalon S, Feuerstein O, Calderon S, Mittleman A, Kaffe I. Detection of cavitated carious lesions in approximal tooth surfaces by ultrasonic caries detector. Oral Surg Oral Med Oral Pathol Oral Radiol Endodontol. 2007;103:109–13.

    Article  Google Scholar 

  61. Zakian CM, Taylor AM, Ellwood RP, Pretty IA. Occlusal caries detection by using thermal imaging. J Dent. 2010;38:788–95.

    Article  CAS  PubMed  Google Scholar 

  62. Ashtiani GH, Sabbagh S, Moradi S, Azimi S, Ravaghi V. Diagnostic accuracy of tele-dentistry in screening children for dental caries by community health workers in a lower-middle-income country. Int J Paediatr Dent. 2024;34:567–75.

    Article  PubMed  Google Scholar 

  63. Kopycka-Kedzierawski DT, Billings RJ, McConnochie KM. Dental screening of preschool children using teledentistry: a feasibility study. Pediatr Dent. 2007;29:209–13.

    PubMed  Google Scholar 

  64. Mola ME, Çoğulu D, Eden E, Topaloğlu A. Is teledentistry as effective as clinical dental diagnosis in pediatric patients? Int J Paediatr Dent. 2025;35:783–91.

Download references

Author information

Authors and Affiliations

Authors

Contributions

SNB conceptualized the study, contributed to the study design, data extraction, analysis, and wrote the first draft of the manuscript. AAD assisted in data collection, analysis, and critically reviewed and revised the manuscript. NHA provided guidance on the methodological framework, supervised the study, and contributed to the manuscript’s final revision. SWP contributed to the study design and provided expert input in data interpretation and manuscript revision. MIK contributed to the study design, supervised the overall project, and was involved in the final review and editing of the manuscript.

Corresponding author

Correspondence to Mohmed Isaqali Karobari.

Ethics declarations

Competing interests

The authors declare no competing interests.

Additional information

Publisher’s note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Supplementary information

Rights and permissions

Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Basheer, S.N., Daghrery, A.A., Albar, N.H. et al. Emerging trends in the early diagnosis of dental caries: a scoping review of artificial intelligence, digital diagnostics, and teledentistry. Evid Based Dent (2026). https://doi.org/10.1038/s41432-026-01207-1

Download citation

  • Received:

  • Accepted:

  • Published:

  • Version of record:

  • DOI: https://doi.org/10.1038/s41432-026-01207-1

Search

Quick links