Fig. 6
Selection pressure and evolutionary pathway for sites 259 (a) and 691 (b) of the bat AAV 10HB capsid gene. The full-length dependovirus capsid coding sequences were subjected to recombination analysis to be split into segments without recombination. Segments 2290–2535 (a) and 6766–7074 (b) were used for MEME analysis [31]. Branches are colored according to the magnitude of the empirical Bayes factor (EBF) for the event of positive selection: red—evidence for positive selection, teal—evidence for neutral evolution or negative selection, black—no information. The amino acid residue for each branch was demonstrated at the root, and the replacements inferred as positive selection were displayed on top of or adjacent to the branches
