Fig. 1: SRCP1 reduces insoluble mutant SOD1 protein.

HEK293 cells expressing G85R SOD1 or A4V SOD1 showed reduced insoluble SOD1 protein upon co-transfection of SRCP1. Expression of wildtype SOD1 does not induce protein aggregation, and expression of SRCP1 had no effect. N = 2.