Fig. 5: Gene therapy foam given prior to radiotherapy enhances treatment efficacy.
From: Drinkable gene therapy foam for the treatment of constrictive esophageal carcinoma
a Experimental schedule to measure the therapeutic benefit of combining gene therapy foam with radiation therapy. The number of OACM5.1 C esophageal carcinoma cells in tumor plugs of our test system was threefold higher, compared to experiments in Figs. 2–4. b Bioluminescence imaging of luciferase expressing OACM5.1 C esophageal tumors isolated from esophageal tubes post treatment. Tumor plugs from 5 independent replicates are shown. c Summary plots showing differences in anti-tumor activity (luciferase signals). Pairwise difference between the groups were statistically analyzed using the unpaired, two-tailed Student’s t test. P < 0.05 was considered significant.
