Table 2 Frequencies of MICA/NKG2D polymorphisms in the SpA population
From: MICA and NKG2D variants as risk factors in spondyloarthritis: a case–control study
n (%) | OR (95% CI) | P | ORadj | |||
|---|---|---|---|---|---|---|
C | P | |||||
MICA 129 | n | 88 | 162 | |||
Met/Met, Met/Val | 41 (47) | 131 (80) | 4.84 (2.75–8.67) | 5 × 10−08 | ns | |
Val/Val | 47 (53) | 31 (19) | 0.20 (0.11–0.37) | 2 × 10−08 | ns | |
MICA A5.1 | n | 90 | 161 | |||
abs | 29 (32) | 85 (53) | 2.16 (1.10–4.30) | 2 × 10−05 | ns | |
Hetero | 41 (46) | 68 (43) | 0.56 (0.32–0.99) | 3 × 10−05 | ns | |
Homo | 20 (22) | 9 (6) | 0.15 (0.06–0.36) | 6 × 10−05 | ns | |
NKC3 | n | 90 | 160 | |||
C/C | 41 (46) | 27 (17) | 0.24 (0.13–0.44) | 1 × 10−06 | 0.14 (0.06–0.33) | |
G/G, G/C | 49 (54) | 133 (83) | 4.12 (2.33–7.47) | 2 × 10−06 | 6.73 (3.04–16.6) | |
NKC4 | n | 124 | 161 | |||
T/T | 6 (5) | 8 (5) | 1.03 (0.35–3.19) | ns | ns | |
C/C, C/T | 118 (95) | 153 (95) | 0.97 (0.31–2.87) | ns | ns | |
